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People with negative mono tests and few or no reactive lymphocytes may be infected by another microorganism that is causing symptoms, such as a. CDC. According to the Mayo Clinic, results for the monospot test, a typical blood test for mononucleosis, come back within a day.

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Medscape Reference [On-line information]. It spreads from person to person through contact with saliva Vorvick, L. (2012 May 15). Mono-like symptoms can be seen in infections other than Epstein-Barr virus. You stand an approximately 25 percent chance of getting a false-negative test result if you are tested within the first week of symptom onset. Cunha, B. Images provided by The Nemours Foundation, iStock, Getty Images, Veer, Shutterstock, Heterophile antibodies decline after the sixth week of illness, and the mono test will become negative as the infection resolves.

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protect yourself by avoiding close contact with anyone who has it. The diagnosis of infectious mononucleosis (mono) is usually made based on the symptoms, findings in a physical examination, and blood tests. MedlinePlus: Infectious Mononucleosis Pagana, Kathleen D. & Pagana, Timothy J. An enlarged spleen can Cases often happen in teens and young adults. fluids. To detect and help diagnose infectious mononucleosis (mono), When a person, especially an adolescent, has symptoms of mononucleosis, including fever, sore throat, swollen glands, and fatigue, A blood sample drawn from pricking of your fingertip or from a vein in your arm. If you have a sore throat, it is likely that a rapid strep test will be performed. It also spreads through coughing and sneezing, or when people share something with Blood. and resting as much as you need to, you will soon be back to normal, usually within Harrison's Principles of Internal Medicine, 16th Edition, McGraw Hill, Pp1046-1048.

Pp. Philadelphia, PA: Saunders Elsevier: 2007, Pp 555-556. What to Know About an Upper Respiratory Infection, Penicillin VK: Uses, Side Effects, Dosages, Precautions, Beyond Zika: What to Know About Mosquito-Borne Diseases, can appear much like the symptoms of strep throat, Clinical differentiation of infectious mononucleosis that is caused by Epstein-Barr virus or cytomegalovirus: A single-center case-control study in Japan, https://www.cdc.gov/epstein-barr/laboratory-testing.html. Accessed May 2009. Pp 683-684. You may be tested for cytomegalovirus or Toxoplasma antibodies.

Ebell, M. (2004 October 1). Omori, M. (Updated 2012 May 23). All rights reserved. Accessed June 13, 2016.

For more information, visit the Centers for Disease Control and Prevention's web page on Chronic Fatigue Syndrome. Centers for Disease Control and Prevention.

What Should I Know About Epstein-Barr Virus?

Your doctor will usually order a complete blood count (CBC) and an antibody test. Get our printable guide for your next doctor's appointment to help you ask the right questions. Aronson MD, Auwaerter PG. utensils to yourself. It can also be positive in people with lymphoma, lupus, and some gastrointestinal cancers, although it is not used as a diagnostic or screening tool for these conditions. To diagnose mono, doctors do an exam to check for things like swollen tonsils and Mononucleosis.

Its most common symptoms are sometimes mistaken for strep

Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003454.htm. Hirsch, L. (Reviewed 2011 January). Cases often happen in teens and young adults. While the Centers for Disease Control (CDC) no longer recommends the ​monospot test, many guidelines still encourage using this test to help identify the cause of mono.

Mono can make the spleen swell for a few weeks or longer. © 1995-document.write(KHcopyDate); The Nemours Foundation. Although the symptoms of infectious mononucleosis usually go away in 1 or 2 months, EBV remains inactive in a few cells in the body for the rest of the person's life.
Available online at http://kidshealth.org/parent/infections/common/mono.html. Accessed November 2012. (Oct 2015) Cunha, B. Medscape.

Epstein-Barr Virus and Infectious Mononucleosis. This population is rarely tested, however, because they do not usually have symptoms of infectious mononucleosis. transfusions, but this is much less common. But you can help The mono test is primarily ordered when a person, especially a teen or young adult, has symptoms that a healthcare practitioner suspects are due to infectious mononucleosis. and even if they had no symptoms. Available online at http://emedicine.medscape.com/article/222040-overview. Mononucleosis tests are blood tests to look for antibodies that indicate mononucleosis (mono), which is usually caused by the Epstein-Barr virus (EBV).The antibodies are made by the immune system to fight an infection.. Mono tests include: Monospot test (heterophil test). Available online at http://www.cdc.gov/ncidod/diseases/ebv.htm. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000591.htm. If they seem to linger or get worse, or if you have any other questions, call You will also have fewer of the other predominant type of white cells, neutrophils, and you may have a lower than usual platelet count. UpToDate. 2019;25(6):431-436. doi:10.1016/j.jiac.2019.01.012, Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved.

Walk-ins are also welcome. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112034/. spit on it (like a straw, drinking glass, eating utensil, or toothbrush). Infants and young kids infected with EBV usually (Updated 2008 October 17). If a mono test is negative and suspicion it still high, then a test specific for EBV antibodies is usually performed. Some of the more common signs and symptoms of mono include: Some people may experience additional signs and symptoms such as: The test may be repeated when it is initially negative but suspicion of mono remains high. eMedicine [On-line information]. Monospot tests can be false-negative about 10 percent to 15 percent of the time, particularly in the early stages of the illness. This can help your doctor make a diagnosis if the symptoms don't go away on their own by day 10. Centers for Disease Control and Prevention: Epstein-Barr Virus and Infectious Mononucleosis, Combatting Modern Slavery and Human Trafficking Statement, Swollen glands in the neck and/or armpits, If symptoms and reactive lymphocytes are present but the mono test is negative, then it may be too early to detect the heterophile antibodies or the affected person may be one of a small percentage of people who do not make heterophile antibodies. National Center for Infectious Diseases. Don't do any strenuous activities until your doctor an enlarged liver or spleen, common signs of the infection.
Mononucleosis. Stamford, Conn.: Appleton & Lang, 1996. Available online at http://www.aafp.org/afp/20041001/1279.html. Pagana, K. D. & Pagana, T. J. Mononucleosis. Smith, D. S. (Updated 2008 September 3). You should note the timeline of the symptoms, including when you or your child first started feeling sick, which symptoms developed, and how long they have lasted. For these reasons, it is almost impossible to prevent spreading the virus and nearly everyone will have had an EBV infection, but not necessarily mono, by the time that they are 40 years old. says it's OK. Your doctor will look at your symptoms and your age (since people infected with EBV are more likely to develop mono if they are a teenager or young adult). For fever and aching muscles, try taking acetaminophen People who've been infected carry the virus for life, even after symptoms stop These include a high fever (101.5 degrees or more), pain in the abdomen, severely swollen throat or tonsils, difficulty breathing or swallowing, limb weakness, or a severe headache. Accessed May 2009. These tests can indicate whether a person is susceptible to EBV, has had a recent infection, has had EBV infection in the past, or has a reactivated EBV infection. Accessed November 2012. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Mononucleosis (pronounced: mah-no-noo-klee-OH-sus), or infectious mononucleosis, Influenza can also mimic some of the symptoms of mono but usually doesn't produce swollen neck glands. The best treatment for mono is plenty of rest and fluids, especially early in the have very mild symptoms or none at all. (© 2007). Strep throat usually responds quickly to antibiotics, while they have no effect on mono. Your blood may be analyzed in a laboratory for antibodies, although this test isn't strictly needed for a diagnosis of infectious mononucleosis.

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